Jerod Denton : rechercher sur Z-Library

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Articles (46)
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Alternative splicing of N- and C-termini of a C. elegans ClC channel alters gating and sensitivity to external Cl− and H+

Jerod Denton, Keith Nehrke, Eric Rutledge, Rebecca Morrison, Kevin Strange

Journal:

The Journal of Physiology

Année:

2004

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2004

55: Rational Synthesis of a Selective Renal Outer Medullary Potassium Channel (ROMK) Antagonist

Gautam Bhave, Brian A. Chauder, Rishin Kadakia, Eric S. Dawson, Craig W. Lindsley, C. David Weaver, Jerod S. Denton

Journal:

American Journal of Kidney Diseases

Année:

2010

Langue:

english

Fichier:

PDF, 68 KB

english, 2010

Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis

Jerod Scott Denton, David Aaron Jacobson

Journal:

Trends in Endocrinology & Metabolism

Année:

2012

Langue:

english

Fichier:

PDF, 818 KB

english, 2012

Carboxy Terminus Splice Variation Alters ClC Channel Gating and Extracellular Cysteine Reactivity

He, Liping, Denton, Jerod, Nehrke, Keith, Strange, Kevin

Journal:

Biophysical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 571 KB

english, 2006

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

Raphemot, Rene, Weaver, C. David, Denton, Jerod S.

Journal:

Journal of Visualized Experiments

Année:

2013

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2013

ML297 (VU0456810), the First Potent and Selective Activator of the GIRK Potassium Channel, Displays Antiepileptic Properties in Mice

Kaufmann, Kristian, Romaine, Ian, Days, Emily, Pascual, Conrado, Malik, Adam, Yang, Liya, Zou, Bende, Du, Yu, Sliwoski, Greg, Morrison, Ryan D., Denton, Jerod, Niswender, Colleen M., Daniels, J. Scott

Journal:

ACS Chemical Neuroscience

Année:

2013

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2013

Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics

Swale, Daniel R, Kharade, Sujay V, Denton, Jerod S

Journal:

Current Opinion in Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 1012 KB

english, 2014

Chemical Synthesis of a Highly Selective Probe of the Renal Outer Medullary Potassium Channel (ROMK)

Denton, Jerod S., Chauder, Brian A., Kadakia, Rishin, Dawson, Eric S., Lindsley, Craig W., Weaver, C. David, Bhave, Gautam

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 36 KB

english, 2010

Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes

Bruehl, Stephen, Denton, Jerod S., Lonergan, Daniel, Koran, Mary Ellen, Chont, Melissa, Sobey, Christopher, Fernando, Shanik, Bush, William S., Mishra, Puneet, Thornton-Wells, Tricia A.

Journal:

PAIN®

Année:

2013

Langue:

english

Fichier:

PDF, 324 KB

english, 2013

Cell Cycle- and Swelling-Induced Activation of a Caenorhabditis elegans ClC Channel Is Mediated by CeGLC-7α/β Phosphatases

Eric Rutledge, Jerod Denton and Kevin Strange

Journal:

The Journal of Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2002

Development and Validation of Fluorescence-Based and Automated Patch Clamp–Based Functional Assays for the Inward Rectifier Potassium Channel Kir4.1

Raphemot, Rene, Kadakia, Rishin J., Olsen, Michelle L., Banerjee, Sreedatta, Days, Emily, Smith, Stephen S., Weaver, C. David, Denton, Jerod S.

Journal:

Assay and Drug Development Technologies

Année:

2013

Langue:

english

Fichier:

PDF, 671 KB

english, 2013

Computational and Functional Analyses of a Small-Molecule Binding Site in ROMK

Swale, Daniel R., Sheehan, Jonathan H., Banerjee, Sreedatta, Husni, Afeef S., Nguyen, Thuy T., Meiler, Jens, Denton, Jerod S.

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 4.13 MB

english, 2015

ROMK (Kir1.1) pharmacology comes of age

Kharade, Sujay V, Swale, Daniel R, Denton, Jerod S

Journal:

Channels

Année:

2015

Langue:

english

Fichier:

PDF, 729 KB

english, 2015

Localization and role of inward rectifier K+ channels in Malpighian tubules of the yellow fever mosquito Aedes aegypti

Piermarini, Peter M., Dunemann, Sonja M., Rouhier, Matthew F., Calkins, Travis L., Raphemot, Rene, Denton, Jerod S., Hine, Rebecca M., Beyenbach, Klaus W.

Journal:

Insect Biochemistry and Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 3.27 MB

english, 2015

The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating

Fallen, Katherine, Banerjee, Sreedatta, Sheehan, Jonathan, Addison, Daniel, Lewis, L. Michelle, Meiler, Jens, Denton, Jerod S.

Journal:

Channels

Année:

2009

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2009

Druggability of the inward rectifier family: a hope for rare channelopathies?

Denton, Jerod S

Journal:

Future Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 927 KB

english, 2014

Targeting renal epithelial channels for the control of insect vectors

Beyenbach, Klaus W, Yu, Yasong, Piermarini, Peter M, Denton, Jerod

Journal:

Tissue Barriers

Année:

2015

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2015

ROMK Inhibitor Actions in the Nephron Probed with Diuretics

Kharade, Sujay V., Flores, Daniel, Lindsley, Craig W, Satlin, Lisa M., Denton, Jerod S.

Journal:

AJP: Renal Physiology

Année:

2015

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2015

The shifting landscape of K ATP channelopathies and the need for ‘sharper’ therapeutics

Kharade, Sujay V, Nichols, Colin, Denton, Jerod S

Journal:

Future Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2016

Pharmacological Correction of Trafficking Defects in ATP-Sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations

Martin, Gregory M., Rex, Emily A., Devaraneni, Prasanna, Denton, Jerod S., Boodhansingh, Kara E., DeLeon, Diva D., Stanley, Charles A., Shyng, Show-Ling

Journal:

Journal of Biological Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2016

Dynamic expression of genes encoding subunits of inward rectifier potassium (Kir) channels in the yellow fever mosquito Aedes aegypti

Yang, Zhongxia, Statler, Bethanie-Michelle, Calkins, Travis L., Alfaro, Edna, Esquivel, Carlos J., Rouhier, Matthew F., Denton, Jerod S., Piermarini, Peter M.

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Année:

2017

Langue:

english

Fichier:

PDF, 883 KB

english, 2017

Pore polarity and charge determine differential block of Kir1.1 and Kir7.1 potassium channels by the small-molecule inhibitor VU590

Kharade, Sujay, Sheehan, Jonathan, Figueroa, Eric, Meiler, Jens, Denton, Jerod

Journal:

Molecular Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2017

Plight of the pore polar bar(rier)

Denton, Jerod S., Kharade, Sujay V.

Journal:

Channels

Année:

2017

Langue:

english

Fichier:

PDF, 776 KB

english, 2017

Abnormal Electroretinogram after Kir7.1 Channel Suppression Suggests Role in Retinal Electrophysiology

Shahi, Pawan K., Liu, Xinling, Aul, Bryce, Moyer, Andrea, Pattnaik, Akshita, Denton, Jerod, Pillers, De-Ann M., Pattnaik, Bikash R.

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 3.91 MB

english, 2017

Eliciting Renal Failure in Mosquitoes with a Small-Molecule Inhibitor of Inward-Rectifying Potassium Channels

Raphemot, Rene, Rouhier, Matthew F., Hopkins, Corey R., Gogliotti, Rocco D., Lovell, Kimberly M., Hine, Rebecca M., Ghosalkar, Dhairyasheel, Longo, Anthony, Beyenbach, Klaus W., Denton, Jerod S., Pier

Journal:

PLoS ONE

Année:

2013

Langue:

english

Fichier:

PDF, 620 KB

english, 2013

Malpighian Tubules as Novel Targets for Mosquito Control

Piermarini, Peter, Esquivel, Carlos, Denton, Jerod

Journal:

International Journal of Environmental Research and Public Health

Année:

2017

Langue:

english

Fichier:

PDF, 3.47 MB

english, 2017

Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-gated, Inwardly-rectifying, Potassium (GIRK) Channels

Kozek, Krystian A, Du, Yu, Sharma, Swagat, Prael, Francis J, Spitznagel, Brittany D, Kharade, Sujay V., Denton, Jerod S., Hopkins, Corey R., Weaver, C. David

Journal:

ACS Chemical Neuroscience

Année:

2018

Langue:

english

Fichier:

PDF, 866 KB

english, 2018

Inward rectifier potassium (Kir) channels in the soybean aphid Aphis glycines: Functional characterization, pharmacology, and toxicology

Piermarini, Peter M., Inocente, Edna Alfaro, Acosta, Nuris, Hopkins, Corey R., Denton, Jerod S., Michel, Andrew P.

Journal:

Journal of Insect Physiology

Année:

2018

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2018

Discovery, Characterization, and Structure?Activity Relationships of an Inhibitor of Inward Rectifier Potassium (Kir) Channels with Preference for Kir2.3, Kir3.X, and Kir7.1

Raphemot, Rene, Lonergan, Daniel F., Nguyen, Thuy T., Utley, Thomas, Lewis, L. Michelle, Kadakia, Rishin, Weaver, C. David, Gogliotti, Rocco, Hopkins, Corey, Lindsley, Craig W., Denton, Jerod S.

Journal:

Frontiers in Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2011

G protein–coupled receptors differentially regulate glycosylation and activity of the inwardly rectifying potassium channel Kir7.1

Carrington, Sheridan, Hernandez, Ciria, Swale, Daniel, Aluko, Oluwatosin A., Denton, Jerod S., Cone, Roger

Journal:

Journal of Biological Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2018

Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval Aedes aegypti

Rusconi Trigueros, Renata, Hopkins, Corey, Denton, Jerod, Piermarini, Peter

Journal:

Insects

Année:

2018

Langue:

english

Fichier:

PDF, 703 KB

english, 2018

Luminal l -alanine stimulates exocytosis at the K + -conductive apical membrane of Aplysia enterocytes

Denton, Jerod, Boahene, Derek, Moran, William M.

Journal:

American journal of physiology. Cell physiology

Année:

1998

Fichier:

PDF, 255 KB

1998

A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel

Strange, Kevin, Yamada, Toshiki, Denton, Jerod S.

Journal:

The Journal of General Physiology

Année:

2019

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2019

Luminal l -alanine stimulates exocytosis at the K + -conductive apical membrane of Aplysia enterocytes

Denton, Jerod, Boahene, Derek, Moran, William M.

Journal:

American journal of physiology. Cell physiology

Année:

1998

Langue:

english

Fichier:

PDF, 255 KB

english, 1998

Intracellular H + regulates the α-subunit of ENaC, the epithelial Na + channel

Chalfant, Michael L., Denton, Jerod S., Berdiev, Bakhram K., Ismailov, Iskander I., Benos, Dale J., Stanton, Bruce A.

Journal:

American journal of physiology. Cell physiology

Année:

1999

Langue:

english

Fichier:

PDF, 233 KB

english, 1999

Discovery and characterization of 2-nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)anilines as novel inhibitors of the Aedes aegypti Kir1 (AeKir1) channel

Aretz, Christopher, Morwitzer, M Jane, Sanford, Austin, Hogan, Alicia M, Portillo, Madalene, Kharade, Sujay V, Kramer, Meghan, Mcarthey, James, Trigueros, Renata R, Piermarini, Peter M., Denton, Jerod

Journal:

ACS Infectious Diseases

Année:

2019

Fichier:

PDF, 683 KB

2019

Towards a TREK-1/2 (TWIK-Related K+ Channel 1 and 2) dual activator tool compound:multi-dimensional optimization of BL-1249

Iwaki, Yuzo, Yashiro, Kentaro, Kokubo, Masaya, Mori, Takahiro, Wieting, Joshua M., McGowan, Kevin M, Bridges, Thomas M., Engers, Darren W., Denton, Jerod S., Kurata, Haruto, Lindsley, Craig W.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2019

Langue:

english

Fichier:

PDF, 393 KB

english, 2019

CysLT1 receptor antagonists Pranlukast and Zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor

Figueroa, Eric E., Kramer, Meghan, Strange, Kevin, Denton, Jerod S.

Journal:

American journal of physiology. Cell physiology

Année:

2019

Langue:

english

Fichier:

PDF, 762 KB

english, 2019

The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel

Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.

Journal:

Physiological Reports

Année:

2019

Langue:

english

Fichier:

PDF, 962 KB

english, 2019

The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel

Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.

Journal:

Physiological Reports

Année:

2019

Fichier:

PDF, 962 KB

2019

Functional and Pore Properties of the LRRC8A Homomeric Channel are Distinct from Those of LRRC8 Chimeras and Heteromres

Yamada, Toshiki, Denton, Jerod S., Strange, Kevin

Journal:

Biophysical Journal

Année:

2020

Langue:

english

Fichier:

PDF, 46 KB

english, 2020

Development of Small-Molecule Inhibitors of Proton-Activated Chloride Channels

Figueroa, Eric E., Denton, Jerod S.

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 45 KB

2020

CysLT1 Receptor Antagonists Pranlukast and Zafirlukast Inhibit LRRC8-Mediated Volume Regulated Anion Channels Independently of the Receptor

Figueroa, Eric E., Denton, Jerod S.

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 64 KB

2020

Lactate activation of Î±-cell KATP channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca2+ entry

Zaborska, Karolina E., Dadi, Prasanna K., Dickerson, Matthew T., Nakhe, Arya Y., Thorson, Ariel S., Schaub, Charles M., Graff, Sarah M., Stanley, Jade E., Kondapavuluru, Roy S., Denton, Jerod S., Jaco

Journal:

Molecular Metabolism

Année:

2020

Fichier:

PDF, 1.99 MB

2020

Further SAR on the (phenylsulfonyl)piperazine scaffold as inhibitors of theÂ Aedes aegyptiÂ Kir1 (AeKir) channel and larvicides

Aretz, Christopher, Kharade, Sujay V, Chronister, Keagan, Trigueros, Renata Rusconi, Rodriguez, Erick Martinez, Piermarini, Peter M, Denton, Jerod S, Hopkins, Corey R

Journal:

ChemMedChem

Année:

2020

Fichier:

PDF, 1.02 MB

2020

VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons

Spitznagel, Brittany D., Mishra, Nigam M., Qunies, Alshaimaâa M., Prael, Francis J., Du, Yu, Kozek, Krystian A., Lazarenko, Roman M., Denton, Jerod S., Emmitte, Kyle A., Weaver, C. David

Journal:

ACS Chemical Neuroscience

Année:

2020

Fichier:

PDF, 2.87 MB

2020